Seizure Detection Using Deep Learning, Information Theoretic Measures and Factor Graphs

Epilepsy is a common neurological disorder that disrupts normal electrical activity in the brain causing severe impact on patients’ daily lives. Accurate seizure detection based on long-term time-series electroencephalogram (EEG) signals has gained vital importance for epileptic seizure diagnosis. However, visual analysis of these recordings is a time-consuming task for neurologists. Therefore, the purpose of this thesis is to propose an automatic hybrid model-based /data-driven algorithm that exploits inter-channel and temporal correlations. Hence, we use mutual information (MI) estimator to compute correlation between EEG channels as spatial features and employ a carefully designed 1D convolutional neural network (CNN) to extract additional information from raw EEGs. Then, seizure probabilities from combined features of MI estimator and CNN are applied to factor graphs to learn factor nodes. The performance of the algorithm is evaluated through measuring different parameters as well as comparing with previous studies. On CHB-MIT dataset, our generalized algorithm achieves state-of-the-art performance

Efficient Epileptic Seizure Detection Using CNN-Aided Factor Graphs

We propose a computationally efficient algorithm for seizure detection. Instead of using a purely data-driven approach, we develop a hybrid model-based/data-driven method, combining convolutional neural networks with factor graph inference. On the CHB-MIT dataset, we demonstrate that the proposed method can generalize well in a 6 fold leave-4-patient-out evaluation. Moreover, it is shown that our algorithm can achieve as much as 5% absolute improvement in performance compared to previous data-driven methods. This is achieved while the computational complexity of the proposed technique is a fraction of the complexity of prior work, making it suitable for real-time seizure detection

CNN-AIDED FACTOR GRAPHS WITH ESTIMATED MUTUAL INFORMATION FEATURES FOR SEIZURE DETECTION

We propose a convolutional neural network (CNN) aided factor graphs assisted by mutual information features estimated by a neural network for seizure detection. Specifically, we use neural mutual information estimation to evaluate the correlation between different electroencephalogram (EEG) channels as features. We then use a 1D-CNN to extract extra features from the EEG signals and use both features to estimate the probability of a seizure event. Finally, learned factor graphs are employed to capture the temporal correlation in the signal. Both sets of features from the neural mutual estimation and the 1D-CNN are used to learn the factor nodes. We show that the proposed method achieves state-of-the-art performance using 6-fold leave-four-patients-out cross-validation